Addressing overtreatment of screen detected DCIS; the LORIS trial.

Addressing overtreatment of screen detected DCIS; the LORIS

Overdiagnosis, and thus overtreatment, are inevitable consequences of most screening programmes; identification of ways of minimising the impact of overdiagnosis demands new prospective research, in particular the need to separate clinically relevant lesions that require active treatment from those that can be safely left alone or monitored and only need treated if they change characteristics. ...

Detection of DCIS and reduced invasive interval cancers.

When breast screening began in the UK, such was the uncertainty concerning the benefi ts and harms of detecting ductal carcinoma in situ (DCIS) that national guidelines specifi ed an upper limit as well as a lower limit for detection by individual screening centres. This was only changed when an association was shown between DCIS detection and small invasive cancer detection in the National Hea...

Addressing Overtreatment in DCIS: What Should Physicians Do Now?

Trends in Detection of Invasive Cancer and Ductal Carcinoma In Situ at Biennial Screening Mammography in Spain: A Retrospective Cohort Study

BACKGROUND Breast cancer incidence has decreased in the last decade, while the incidence of ductal carcinoma in situ (DCIS) has increased substantially in the western world. The phenomenon has been attributed to the widespread adaption of screening mammography. The aim of the study was to evaluate the temporal trends in the rates of screen detected invasive cancers and DCIS, and to compare the ...

Re: Detection of ductal carcinoma in situ in women undergoing screening mammography.

BACKGROUND With the large number of women having mammography-an estimated 28.4 million U.S. women aged 40 years and older in 1998-the percentage of cancers detected as ductal carcinoma in situ (DCIS), which has an uncertain prognosis, has increased. We pooled data from seven regional mammography registries to determine the percentage of mammographically detected cancers that are DCIS and the ra...